Multi-digit tactile perception I: motion integration benefits for tactile trajectories presented bimanually

Interactions with objects involve simultaneous contact with multiple, not necessarily adjacent, skin regions. While advances have been made in understanding the capacity to selectively attend to a single tactile element among distracting stimulations, here, we examine how multiple stimulus elements are explicitly integrated into an overall tactile percept. Across four experiments, participants averaged the direction of two simultaneous tactile motion trajectories of varying discrepancy delivered to different fingerpads. Averaging performance differed between within- and between-hands conditions in terms of sensitivity and precision but was unaffected by somatotopic proximity between stimulated fingers. First, precision was greater in between-hand compared to within-hand conditions, demonstrating a bimanual perceptual advantage in multi-touch integration. Second, sensitivity to the average direction was influenced by the discrepancy between individual motion signals, but only for within-hand conditions. Overall, our experiments identify key factors that influence perception of simultaneous tactile events. In particular, we show that multi-touch integration is constrained by hand-specific rather than digit-specific mechanisms

Multi-Method Learning and Assimilation

Considering the wide range of possible behaviors to be acquired for domestic robots, applying a single learning method is clearly insufficient. In this paper, we propose a new strategy for behavior acquisition for domestic robots where the behaviors are acquired using multiple differing learning methods that are subsequently incorporated into a common behavior selection system, enabling them to be performed in appropriate situations. An example implementation of this strategy applied to the entertainment humanoid robot QRIO is introduced and the results are discussed

Binding interactions of the peripheral stalk subunit isoforms from human V-ATPase

<p>The mammalian peripheral stalk subunits of the vacuolar-type H⁺-ATPases (V-ATPases) possess several isoforms (C1, C2, E1, E2, G1, G2, G3, a1, a2, a3, and a4), which may play significant role in regulating ATPase assembly and disassembly in different tissues. To better understand the structure and function of V-ATPase, we expressed and purified several isoforms of the human V-ATPase peripheral stalk: E1G1, E1G2, E1G3, E2G1, E2G2, E2G3, C1, C2, H, a1_NT, and a2_NT. Here, we investigated and characterized the isoforms of the peripheral stalk region of human V-ATPase with respect to their affinity and kinetics in different combination. We found that different isoforms interacted in a similar manner with the isoforms of other subunits. The differences in binding affinities among isoforms were minor from our <i>in vitro</i> studies. However, such minor differences from the binding interaction among isoforms might provide valuable information for the future structural-functional studies of this holoenzyme.</p> <p>Schematic model of human V-ATPase illustrating the mode of binding interactions at the peripheral stalk region.</p